You may have read about forskolin for weight loss from the media recently, as it has been featured in a variety of publications because of its weight loss properties. Dr Oz even included it in their “best belly busting supplements” list, due to its thermogenic properties.
In our report you’ll find out how this new substance works, whether its safe to enjoy, and even more importantly we’ll review its usefulness as a weight loss aid.
Coleus forskohlii, also called plectranthus barbatus or Indian Coleus, is actually a tropical plant that is closely relevant to the coleus species.
Coleus forskohlii is of particular interest to us due to the potential as a weight loss aid and antioxidant.
Forskolin, also referred to as coleonol, can be a compound which occurs naturally in Coleus forskohlii and has been used in the research into cell physiology to activate the enzyme adenylyl cyclase, along with improving the intracellular degrees of cyclic AMP, or cAMP.
cAMP plays a vital role in cell signaling, in addition to directly impacting how cells reply to various hormonal stimuli, affecting hypothalamic and pituitary function.
What this basically means is the fact that Forskolin helps cells contact one another, greatly increasing hormonal function and essentially telling our bodies to make more of an enzyme known as hormone sensitive lipase.
If you’ve ever heard the saying “lipid” then you can probably guess that hormone sensitive lipase has something connected with body fat in our bodies, which happens to be exactly right!
It also appears as if the upregulation, or boost in manufacture of cAMP features a knock-on effect, causing an increased manufacture of thyroid hormone which, again, enables you to stimulate the metabolism and cause great fat loss.
This could all sound a little bit complicated but all we need to know at this point is the fact that Forskolin causes our bodies to produce more lipolytic, or fat-burning enzymes, and also more fat-burning hormones.
Even if this all looks like great news for anyone of us that want to lose weight, let’s dig just a little deeper to determine if this actually results in increased weight loss in real life.
The 1st study we’re going to check out was published from the Journal of Obesity Research in 2005, and set up out to ascertain the body composition and hormonal adaptations devyqky71 with forskolin consumption in overweight and obese men.
This randomized, double-blind, placebo-controlled study took place spanning a 12-week period and involved 30 subjects, with a dosage of 250 mg of 10% forskolin supplement twice daily.
The resulting data with this study looks very promising, with subjects exhibiting the following:
A “significant decrease” in body fat percentage and overall fat mass
A “significant increase” in lean body weight; coupled with
A modification of bone mass, suggesting an increase in bone density
A “significant increase” in free testosterone levels
This points to Forkolin being not simply a pure fat loss supplement but additionally an all natural method for men to boost their testosterone levels, which can lead to less unwanted fat and more lean muscle mass.
The study group concluded with the following statement: “The results indicate that forskolin can be a possible therapeutic agent for your management and management of obesity.”
The studies on the negative effects of Forskolin in ladies is a lot more interesting, starting with one study published within the Journal in the International Society of Sports Nutrition in 2005.
Although “no significant differences” were seen in unwanted fat mass from the subjects, it is very interesting to note how the Forskolin actually seemed to “mitigate gains in body weight,” suggesting that adherence to some sensible diet and physical activity plan might be enough to tip the scales, so to speak, within a more favorable direction.
Some subjects also reported a decrease in fatigue and hunger, and this might have significant implications for folks who are saved to low-calorie diets.
What’s more, they reported that “No clinically significant interactions were found in metabolic markers, blood lipids, muscle and liver enzymes, electrolytes, red cells, white cells, hormones (insulin, TSH, T3, and T4), heartrate, blood pressure, or weekly reports of negative effects.”
Showing the Forskolin seems to be free from any adverse side effects, making it a safe weight loss and weight management aid to the general population.
Topical Forskolin for Spot Reduction
Many individuals have problems with what is commonly known as stubborn fat. In men this typically is found on the lower abdominal and “love handle” regions, with the hips and thighs being of particular notoriety in ladies.
Excess fat spot reduction has long been dismissed by many like a myth, but a number of trials assessed within the Journal of Obesity Research in 1995 used several topical ointments containing Forskolin.
They figured that, “All trials gave significantly more girth loss in the treated thigh. We conclude that topical fat reduction for women’s thighs can be accomplished without diet or exercise.”
One animal study involving mice did observe a difference inside the Cytochrome P450 system, which plays a role in the absorption and metabolism of various types of medication, including but not restricted to blood thinners including Warfarin.
For this reason, it will be best if you consult your doctor before taking a Forskolin supplement in case you are taking any relevant medications.
Other than this we could find no negative effects associated with forskolin for weight loss, and similar findings were present in an investigation published within the Journal in the International Society of Sports Nutrition in 2005 showing that Forskolin looks to be clear of any adverse side effects.
Forskolin seems to show quite a lot of promise from the parts of fat loss and also the decrease in fat gain, as well as being almost entirely free from potential unwanted effects.